Mayim Bialik as Amy Fowler
Of course the incredibly intelligent Amy Fowler makes the list! And guys, Mayim Bialik is probably as smart, or smarter, than her character. Bialik has a B.S. degree in neuroscience, minors in Hebrew and Jewish studies, and also a Ph.D in neuroscience. Yeah, she’s that smart! The 41 year old feminist has earned four nominations for the Primetime Emmy Award.
Simon Helberg as Howard Wolowitz
Meet Howard Wolowitz, an engineer and astronaut who had a very overbearing mother. Eventually he gets hitched to Bernadette and his character development is one for the history books. The 36 year old was also nominated for a Golden Globe for the 2016 film Florence Foster Jenkins. Moreover, Simon Helberg also works as a musician and comedian.